You know there’s a problem when the corpse starts laughing. All morning on the set of Rizzoli & Isles, Angie Harmon and Sasha Alexander have been struggling to get through a morgue scene. The cadaver on the slab has a zipper-like slash across the throat, but it’s ­ Alexander who looks like death. She’s been fighting a cold and losing.

“Man! Can someone get Sasha a Kleenex?” Harmon says to hoots and giggles after Alexander derails another take with a sneeze. The dead woman’s shoulders start jiggling. ­ Alexander tilts her head back in fluish exhaustion and says, “I should probably get stock in Kleenex.”

At least the show is healthy. TV’s hottest crime-solving duo enters Season 4 as the third-best-rated ­series on basic cable. Rizzoli & Isles averaged more than 7.5 million viewers on TNT last season, capped by a finale that, come to think of it, had some major health issues of its own.

After serious reflection (and pressure from her biological mom, Hope), Maura Isles, the erudite, fashion-­forward Boston medical examiner played by Alexander, agreed to give up her kidney anonymously to save the half sister she barely knows. Jane Rizzoli, Maura’s best friend and tough-talking colleague in the Boston Police Department, tried persuading her injured-soldier boyfriend, Casey (Chris Vance), not to go through with potentially life-threatening spine surgery. Meanwhile, Jane’s kid brother, Tommy (Colin Egglesfield), Tommy’s baby, T.J., and a detective had to be dug out of a collapsed building.

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I’ve added the 3 photos of Sasha to the gallery from the most recent promotional shoot.